| 1. George Seton |
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| B: |
1508 |
| P: |
Cunninghame, Ayrshire, Scotland |
| D: |
17 Jul 1549 |
| P: |
Culross, Fife, Scotland |
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| 2. George Seton |
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| B: |
1481 |
| P: |
Eglinton, Kilwinning, Ayrshire, Scotland |
| M: |
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| D: |
9 Sep 1513 |
| P: |
Branxton, Northumberland, England |
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| 4. George Seton |
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| B: |
1449 |
| P: |
Seton, East Lothian, Scotland |
| M: |
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| D: |
6 Apr 1508 |
| P: |
Argyll, Scotland |
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| 3. Janet Hepburn |
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| B: |
1485 |
| P: |
Bothwell, Lanarkshire, Scotland |
| D: |
10 May 1558 |
| P: |
Edinburgh, Midlothian, Scotland |
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| 6. Patrick Hepburn |
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| B: |
1450 |
| P: |
Bothwell, Lanarkshire, Scotland |
| M: |
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| D: |
18 Oct 1508 |
| P: |
Bothwell, Lanarkshire, Scotland |
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| 12. |
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| 7. Janet Douglas |
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| B: |
1461 |
| P: |
Morton, Dumfries-shire, Scotland |
| D: |
21 Feb 1490 |
| P: |
Selkirkshire, Scotland |
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1508 - 1549 (41 years)